美国PeproTech公司是全球最大的重组细胞因子和蛋白生产商之一，始终致力于为生命科学研究开发重组蛋白及相关产品，如今已成为能提供多种高质量细胞因子和重组蛋白，相应的单克隆、多克隆和生物素标记抗体，以及ELISA试剂盒的引领者。PeproTech.的产品涵盖免疫调节蛋白、白介素、集落刺激因子、生长因子、无动物成分的重组蛋白、化学趋化因子、干扰素、脂联素、成纤维生长因子、转化生长因子、肿瘤坏死因子、神经营养素和防御素等诸多生命科学研究领域中重要的生物活性分子。PeproTech公司的产品种类、规格齐全，更新速度快，且价格适中，已广为中国的科研工作者所使用。
为跟踪当今科研发展、满足日益增长的需求，PeproTech公司追求不断创新和与时俱进。PeproTech公司2019年5月推出6种新产品，分别是：
| 类别 |
名称 |
货号 |
规格 |
价格/RMB |
| 无动物成分细胞因子 |
Human IL-18BP Fc |
200-18BP |
20ug |
¥1050 |
| 无动物成分细胞因子 |
Human IL-18BP Fc |
200-18BP |
100ug |
¥2570 |
| 无动物成分细胞因子 |
Human IL-18BP Fc |
200-18BP |
250ug |
¥5920 |
| 无动物成分细胞因子 |
Human IL-18BP Fc |
200-18BP |
500ug |
¥10160 |
| 无动物成分细胞因子 |
Human IL-18BP Fc |
200-18BP |
1000ug |
¥16940 |
| 无动物成分细胞因子 |
Human GITR/TNFRSF18 Fc |
310-22R |
20ug |
￥1,050 |
| 无动物成分细胞因子 |
Human GITR/TNFRSF18 Fc |
310-22R |
100ug |
￥2,570 |
| 无动物成分细胞因子 |
Human GITR/TNFRSF18 Fc |
310-22R |
250ug |
￥5,920 |
| 无动物成分细胞因子 |
Human GITR/TNFRSF18 Fc |
310-22R |
500ug |
￥10,160 |
| 无动物成分细胞因子 |
Human GITR/TNFRSF18 Fc |
310-22R |
1000ug |
￥16,940 |
| 多克隆抗体 |
Rabbit Anti-Human HB-EGF |
500-P329 |
50ug |
￥2,570 |
| 多克隆抗体 |
Rabbit Anti-Human HB-EGF |
500-P329 |
100ug |
￥3,300 |
| 多克隆抗体 |
Rabbit Anti-Human HB-EGF |
500-P329 |
1000ug |
￥26,180 |
| 生物素标记多抗 |
Biotinylated Rabbit Anti-Human HB-EGF |
500-P329BT |
25ug |
￥2,570 |
| 生物素标记多抗 |
Biotinylated Rabbit Anti-Human HB-EGF |
500-P329BT |
50ug |
￥3,300 |
| 生物素标记多抗 |
Biotinylated Rabbit Anti-Human HB-EGF |
500-P329BT |
1000ug |
¥52,360 |
| ELISA试剂盒 |
Human sTRAIL/Apo2L Mini ELISA
Development Kit (ABTS) |
900-M141 |
200tests |
￥1,320 |
| ELISA试剂盒 |
Human IL-7 Mini ELISA Development
Kit (ABTS) |
900-M17 |
200tests |
￥1,320 |
1.无动物成份重组人IL-18BP Fc
产品描述:Interleukin-18 binding protein (IL-18BP) is a constitutively secreted glycoprotein that acts as a natural antagonist for interleukin-18 (IL-18) by preventing interaction between IL-18 and its receptors. Through this binding, IL-18BP neutralizes the proinflammatory role of IL-18 in cell-mediated immune responses, resulting in reduced IFN-γ production by T helper type I cells and inhibition of allospecific cytotoxic T lymphocyte (CTL) activity through augmented natural killer (NK) cell cytotoxicity. As an inhibitor of IL-18 and an essential component of skin homeostasis, IL-18BP has been linked to a variety of diseases, including eczema, asthma, and the autoimmune condition, Crohn’s disease. The upregulation of IL-18BP by keratinocytes expressing the human papillomavirus (HPV) E7 oncoprotein has been shown to decrease IL-18-induced IFN-γ production and IL-18-mediated T cell activation. Elevated levels of IL-18 and IL-18BP, as well as proinflammatory cytokines IFN-γ, TNF-α, IL-1β and IL-8, have been linked to chronic inflammation and observed in macrophages (including Kupffer cells) isolated from lesions and intestinal tissues of Crohn’s disease patients. As a member of the immunoglobulin-like class of receptors, IL-18BP contains a single immunoglobulin (Ig) domain; although two (b and d) of the four identified human isoforms (a-d) contain incomplete domains that greatly reduce their binding affinity.--PeproTech’s CHO cell-derived Recombinant Human IL-18BP Fc is a glycosylated, disulfide-linked homodimer of 792 amino-acid-residues whose monomer consists of a 163-amino-acid portion of secreted IL-18BP fused to the 231-amino-acid length Fc portion of human IgG by two glycine residues. The calculated molecular weight of monomeric CHO cell-derived Recombinant Human IL-18BP Fc is 43.6 kDa; however, due to glycosylation, it migrates at an apparent molecular weight of approximately 60-65 kDa by SDS-PAGE analysis under reducing conditions.
2.无动物成份重组人GITR/TNFRSF18 Fc
产品描述:GITR, also known as tumor necrosis factor receptor superfamily 18 (TNFRSF18), is a member of the receptor family bearing the same name that is expressed on the surfaces of cells involved in both adaptive and innate immunity, including CD4+ T cells, CD8+ T cells, natural killer cells, B cells, macrophages, and dendritic cells. Like all other TNFRSF members, GITR regulates the duration, phenotype, and degree by which the immune system responds to antigens. The National Cancer Institute regards GITR as the 12th most important molecule involved in immunotherapy, as it plays a major role in modulating both inflammatory and immune responses. The receptor has attracted the attention of immunologists for its potential as a costimulatory immune checkpoint molecule in immunotherapy. Expressed in peripheral tissues as well as endothelial cells, GITR inhibits T cell receptor-induced apoptosis via its cross-linking mechanism, thereby creating an environment that promotes T cell longevity and survival. To accomplish this task, GITR initiates signal transduction by activating nuclear factor κB (NF-κB) along with the following specific mitogen-activated protein kinase (MAPK) pathways: extracellular signal-related kinases (ERKs), c-Jun N-terminal kinase (JNK), and p38. Several bone disorders, such as familial expansive osteolysis, autosomal recessive osteopetrosis and Paget’s disease, have been attributed to GITR mutations due to its key role in regulating osteoclast and lymph node development. PeproTech’s CHO cell-derived Recombinant Human GITR/TNFRSF18 Fc is a glycosylated, disulfide-linked homodimer of 738 amino-acid-residues whose monomer consists of a 136-amino-acid extracellular domain fused to the 231-amino-acid length Fc portion of human IgG by two glycine residues. The calculated molecular weight of monomeric CHO cell-derived Recombinant Human GITR/TNFRSF18 Fc is 40.6 kDa; however, due to glycosylation, it migrates at an apparent molecular weight of approximately 45-50 kDa by SDS-PAGE analysis under reducing conditions.
3.兔抗人HB-EGF多抗
产品描述:Produced from sera of-rabbits-immunized with highly pure-Recombinant-Human HB-EGF. Anti-Human HB-EGF-specific antibody was purified-by affinity chromatography employing an immobilized Human HB-EGFmatrix.
4.兔抗人HB-EGF（生物素标记）
产品描述:Produced from sera of-rabbits-immunized with highly pure-Recombinant-Human HB-EGF. Anti-Human HB-EGF-specific antibody was purified-by affinity chromatography and then biotinylated.
5.重组人sTRAIL/Apo2L Mini ELISA试剂盒
产品描述:Human sTRAIL/Apo2L ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant Human sTRAIL/Apo2L in a sandwich ELISA format within the range of 32–2000 pg/ml. Using the ELISA protocol described below, the recommended microplates, reagents and solutions, the components supplied in this kit are sufficient to assay Human sTRAIL/Apo2L in approximately 200 ELISA plate wells.
6.重组人IL-7 Mini ELISA试剂盒
产品描述:Human IL-7 ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant Human IL-7 in a sandwich ELISA format within the range of 32–2000 pg/ml. Using the ELISA protocol described below, the recommended microplates, reagents and solutions, the components supplied in this kit are sufficient to assay Human IL-7 in approximately 200 ELISA plate wells. |
欢迎各位科研工作者前来咨询和订购！
PeproTech将继续支持您的科研工作，祝您工作顺利！
PeproTech(派普泰克)中国代表处
江苏省苏州市工业园区星湖街218号A1北座4楼M10
邮编：215123
电话：0512-6832 5983
全国免费热线：4000053055
企业qq:800053055(在线咨询)
Email：china@peprotech.com
Website：www.peprotech.com |
