- 公司地址
-
上海市浦东新区金桥路27号
邮编：
- 联系电话
- 4008****82登录查看商家电话
- 传真号码
- 电子邮箱
- peprotech.infochina@****mofisher.com登录查看商家邮箱
- 公司网址
- www.peprotech.com
PeproTech 2018年8月发布Human TMIGD2/CD28H、Human sCD8α、Murine IL-10等新品！
发布时间：2018-08-16 15:49 | 点击次数：
美国PeproTech公司是全球最大的重组细胞因子和蛋白生产商之一，始终致力于为生命科学研究开发重组蛋白及相关产品，如今已成为能提供多种高质量细胞因子和重组蛋白，相应的单克隆、多克隆和生物素标记抗体，以及ELISA试剂盒的引领者。PeproTech.的产品涵盖免疫调节蛋白、白介素、集落刺激因子、生长因子、无动物成分的重组蛋白、化学趋化因子、干扰素、脂联素、成纤维生长因子、转化生长因子、肿瘤坏死因子、神经营养素和防御素等诸多生命科学研究领域中重要的生物活性分子。PeproTech公司的产品种类、规格齐全，更新速度快，且价格适中，已广为中国的科研工作者所使用。
1.重组人TMIGD2/CD28H 产品描述:Transmembrane and immunoglobulin domain-containing protein 2 (TMIGD2), or CD28H, is a type I costimulatory transmembrane receptor of the CD28 receptor family that functions as both an adhesion molecule and regulator of T cell function. TMIGD2 is constitutively expressed on naïve T cells and NK cells, although expression is rapidly lost upon stimulation. Interaction with its ligand, B7-H7/HHLA2, co-stimulates T cell proliferation and differentiation, as well as increases cytokine production through the Akt pathway. TMIGD2 is also widely expressed on cells of epithelial and endothelial origin where it regulates cell morphology and cell-cell interaction, reduces cell migration and promotes angiogenesis. The cytoplasmic tail of TMIGD2 interacts with SH3-containing signaling molecules, such as SPIN90, CACNB2, BPAG1 and MIA, to modulate angiogenesis. CHO cell-derived Recombinant Human TMGID2/CD28H Fc is a glycosylated, disulfide-linked homodimer of 361-amino-acid-residues whose monomer consists of the 128-amino-acid extracellular domain fused to the 231-amino-acid length Fc portion of human IgG1 by two glycine residues. The calculated molecular weight of monomeric Recombinant TMIGD2/CD28H Fc is 40.1kDa; however, due to glycosylation, it migrates at an apparent molecular weight of approximately 55-60 kDa by SDS-PAGE analysis under reducing conditions. 2.重组小鼠sCD8α 产品描述:Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T-cell differentiation and activation. CD8 is predominantly expressed on T-cells as a disulfide-linked heterodimer of CD8α and CD8β, where it functions as a co-receptor, along with T-cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules. CD8 exists on the cell surface, where the CD8α chain is essential for binding to MHC-I. CD8 is also expressed on a subset of T-cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8α. Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation. Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells. Differentiation of naïve CD8+ T-cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-β1. PeproTech’s CHO cell-derived Recombinant Human sCD8α is a monomeric glycoprotein of 161 amino acid residues, which corresponds to the extracellular domain of CD8α. Peprotech’s CHO cell-derived Recombinant Human sCD8α has a calculated molecular weight of 17.6 kDa; however, due to glycosylation, it migrates at an apparent molecular weight of approximately 27-29 kDa by SDS-PAGE analysis, under reducing conditions. 3.无动物成份重组小鼠IL-10 产品描述：IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-α. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells. Recombinant Murine IL-10 is an 18.7 kDa protein of 161 amino acid residues. 4.GMP级别重组人VEGF 165 产品描述：VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Recombinant Human VEGF165 is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. 5.兔抗人VAP-1多抗 产品描述： Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human VAP-1. Anti-Human VAP-1-specific antibody was purified by affinity chromatography employing an immobilized Human VAP-1 matrix. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human Adiponectin. Anti-Human Adiponectin-specific antibody was purified by affinity chromatography employing an immobilized Human Adiponectin matrix. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human sIL-4 Receptor α. Anti-Human sIL-4 Receptor α-specific antibody was purified by affinity chromatography employing an immobilized-Human sIL-4 Receptor α matrix. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Murine LIGHT. Anti-Murine LIGHT-specific antibody was purified by affinity chromatography employing an immobilized Murine LIGHT matrix. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human MMP-3. Anti-Human MMP-3-specific antibody was purified by affinity chromatography employing an immobilized MMP-3 matrix. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human BAFF. Anti-Human BAFF-specific antibody was purified by affinity chromatography employing an immobilized Human BAFF matrix. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human TGF-β3. Anti-Human TGF-β3-specific antibody was purified by affinity chromatography employing an immobilized Human TGF-β3 matrix. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human VAP-1. Anti-Human VAP-1-specific antibody was purified by affinity chromatography and then biotinylated. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human Adiponectin. Anti-Human Adiponectin-specific antibody was purified by affinity chromatography and then biotinylated. Preparation:Produced from sera of rabbits immunized with highly pure-Recombinant-Human sIL-4 Receptor α. Anti-Human sIL-4 Receptor α-specific antibody was purified by affinity chromatography and then biotinylated. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human MMP-3. Anti-Human MMP-3-specific antibody was purified by affinity chromatography and then biotinylated. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human BAFF. Anti-Human BAFF-specific antibody was purified by affinity chromatography and then biotinylated. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Murine LIGHT. Anti-Murine LIGHT-specific antibody was purified by affinity chromatography and then biotinylated. Preparation:Produced from sera of rabbits immunized with highly pure Recombinant Human TGF-β3. Anti-Human TGF-β3-specific antibody was purified by affinity chromatography and then biotinylated.
欢迎各位科研工作者前来咨询和订购！ PeproTech将继续支持您的科研工作，祝您工作顺利！ PeproTech(派普泰克)中国代表处 江苏省苏州市玉山路99号钻石广场2幢416室 邮编：215011 电话：0512-6832 5983 全国免费热线：4000053055 企业qq:800053055(在线咨询) Email：china@peprotech.com Website：www.peprotech.com |