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PeproTech 2018年4月发布Human FGF-BP-1,Human MD-2/LY96等12种新品!

发布时间:2018-05-24 18:10 |  点击次数:

       美国PeproTech公司是全球最大的重组细胞因子和蛋白生产商之一,始终致力于为生命科学研究开发重组蛋白及相关产品,如今已成为能提供多种高质量细胞因子和重组蛋白,相应的单克隆、多克隆和生物素标记抗体,以及ELISA试剂盒的世界领导者。PeproTech.的产品涵盖免疫调节蛋白、白介素、集落刺激因子、生长因子、无动物成分的重组蛋白、化学趋化因子、干扰素、脂联素、成纤维生长因子、转化生长因子、肿瘤坏死因子、神经营养素和防御素等诸多生命科学研究领域中重要的生物活性分子。PeproTech公司的产品种类、规格齐全,更新速度快,且价格适中,已广为中国的科研工作者所使用。
     
      为跟踪当今科研发展、满足日益增长的需求,PeproTech公司追求不断创新和与时俱进。PeproTech公司2018年4推出10种新产品,分别是:
类别 名称 货号 规格 价格/RMB
细胞因子 Human FGF-BP-1 100-66-5 5ug ¥1,050.00
细胞因子 Human FGF-BP-1 100-66-25 25ug ¥2,570.00
细胞因子 Human FGF-BP-1 100-66-100 100ug ¥9,900.00
细胞因子 Human FGF-BP-1 100-66-250 250ug ¥18,010.00
细胞因子 Human FGF-BP-1 100-66-500 500ug ¥30,880.00
细胞因子 Human FGF-BP-1 100-66-1000 1000ug ¥51,480.00
细胞因子 Human MD-2/LY96 160-07-10 10ug ¥1,050.00
细胞因子 Human MD-2/LY96 160-07-50 50ug ¥2,570.00
细胞因子 Human MD-2/LY96 160-07-100 100ug ¥3,960.00
细胞因子 Human MD-2/LY96 160-07-250 250ug ¥6,930.00
细胞因子 Human MD-2/LY96 160-07-500 500ug ¥11,880.00
细胞因子 Human MD-2/LY96 160-07-1000 1000ug ¥19,800.00
细胞因子 Human GPR15L 300-71-5 5ug ¥1,050.00
细胞因子 Human GPR15L 300-71-25 25ug ¥2,570.00
细胞因子 Human GPR15L 300-71-100 100ug ¥7,920.00
细胞因子 Human GPR15L 300-71-250 250ug ¥13,860.00
细胞因子 Human GPR15L 300-71-500 500ug ¥23,760.00
细胞因子 Human GPR15L 300-71-1000 1000ug ¥39,600.00
细胞因子 Human PD-1 Fc 310-40-10 10ug ¥1,050.00
细胞因子 Human PD-1 Fc 310-40-50 50ug ¥2,570.00
细胞因子 Human PD-1 Fc 310-40-100 100ug ¥4,620.00
细胞因子 Human PD-1 Fc 310-40-250 250ug ¥8,080.00
细胞因子 Human PD-1 Fc 310-40-500 500ug ¥13,860.00
细胞因子 Human PD-1 Fc 310-40-1000 1000ug ¥23,100.00
无动物成分细胞因子 Animal-Free Recombinant Human IL-5 AF-200-05-2 2ug ¥1,250.00
无动物成分细胞因子 Animal-Free Recombinant Human IL-5 AF-200-05-10 10ug ¥2,830.00
无动物成分细胞因子 Animal-Free Recombinant Human IL-5 AF-200-05-50 50ug ¥5,220.00
无动物成分细胞因子 Animal-Free Recombinant Human IL-5 AF-200-05-100 100ug ¥8,710.00
无动物成分细胞因子 Animal-Free Recombinant Human IL-5 AF-200-05-250 250ug ¥15,240.00
无动物成分细胞因子 Animal-Free Recombinant Human IL-5 AF-200-05-500 500ug ¥26,130.00
无动物成分细胞因子 Animal-Free Recombinant Human IL-5 AF-200-05-1000 1000ug ¥43,560.00
无动物成分细胞因子 Animal-Free Recombinant Human MCP-2 (CCL8) AF-300-15-2 2ug ¥1,250.00
无动物成分细胞因子 Animal-Free Recombinant Human MCP-2 (CCL8) AF-300-15-10 10ug ¥2,830.00
无动物成分细胞因子 Animal-Free Recombinant Human MCP-2 (CCL8) AF-300-15-50 50ug ¥5,220.00
无动物成分细胞因子 Animal-Free Recombinant Human MCP-2 (CCL8) AF-300-15-100 100ug ¥8,710.00
无动物成分细胞因子 Animal-Free Recombinant Human MCP-2 (CCL8) AF-300-15-250 250ug ¥15,240.00
无动物成分细胞因子 Animal-Free Recombinant Human MCP-2 (CCL8) AF-300-15-500 500ug ¥26,130.00
无动物成分细胞因子 Animal-Free Recombinant Human MCP-2 (CCL8) AF-300-15-1000 1000ug ¥43,560.00
GMP级别细胞因子 PeproGMP® Recombinant Human Heregulinβ-1 GMP100-03-50 50ug ¥4,950.00
GMP级别细胞因子 PeproGMP® Recombinant Human Heregulinβ-1 GMP100-03-100 100ug ¥9,240.00
GMP级别细胞因子 PeproGMP® Recombinant Human PDGF-AA GMP100-13A-50 50ug ¥7,920.00
GMP级别细胞因子 PeproGMP® Recombinant Human PDGF-AA GMP100-13A-100 100ug ¥13,200.00
GMP级别细胞因子 PeproGMP® Recombinant Human KGF GMP100-19-50 50ug ¥10,230.00
GMP级别细胞因子 PeproGMP® Recombinant Human KGF GMP100-19-100 100ug ¥19,140.00
GMP级别细胞因子 PeproGMP® Recombinant Human Activin A GMP120-14E-50 50ug ¥7,920.00
GMP级别细胞因子 PeproGMP® Recombinant Human Activin A GMP120-14E-100 100ug ¥13,200.00
多克隆抗体 Anti-Human CRP 500-P242-50 50ug ¥2,570.00
多克隆抗体 Anti-Human CRP 500-P242-100 100ug ¥3,300.00
多克隆抗体 Anti-Human CRP 500-P242-1000 1000ug ¥22,440.00
多克隆抗体 Biotinylated Anti-Human CRP 500-P242BT-25 25ug ¥2,570.00
多克隆抗体 Biotinylated Anti-Human CRP 500-P242BT-50 50ug ¥3,300.00
多克隆抗体 Biotinylated Anti-Human CRP 500-P242BT-1000 1000ug ¥44,880.00

1.重组人FGF-BP-1

产品描述:The Fibroblast Growth Factor (FGF) Superfamily is comprised of multifunctional proteins that serves to regulate several complex biological processes related to the development, restoration, and/or redistribution of prenatal and postnatal tissue, as well as angiogenesis, wound healing, nerve regeneration, chronic inflammation, and cancer growth. Members of the FGF Superfamily function through paracrine, autocrine and intracrine pathways to promote spatial and temporal integrations of several cell responses, such as proliferation, growth, differentiation, and migration. Fibroblast growth factor binding protein 1 (FGF-BP-1) is a secreted glycoprotein, which contains both a heparin-binding domain and a distinct FGF-binding region, that is shed into circulation where it acts as a chaperone molecule for FGFs, most notably FGF-acidic and FGF-basic.  Recombinant Human FGF-BP-1 expressed in E.coli is a 24.0 kDa protein containing 212 amino acid residues.

2.重组人MD-2/LY96

产品描述:Myeloid differentiation protein-2 (MD-2), also referred to as LY69, is an accessory glycoprotein secreted in hematopoietic, nervous, and reproductive tissues at various stages of development where it regulates innate immune responses to microbial pathogens through interaction with the extracellular do mains of TLR-2 and TLR-4. The association of MD-2 with the extracellular domain of TLR-4, which is constitutively expressed in cells of the immune system, localizes TLR-4 to the cell surface and forms the TLR-4/MD-2 receptor complex necessary for signal transduction in response to inflammatory signals.  PeproTech’s HEK293 cell-derived Recombinant Human MD-2/LY96 is a disulfide-linked homodimer whose monomer contains 148 amino acid residues, including a C-terminal His tag, and has a calculated molecular weight of 17.2 kDa.

3.重组人GPR15L

产品描述:GPR15L is a newly identified ligand for GPR15, a member of the G protein-coupled receptor (GPCR) family. Upon ligation, GPR15L acts as a potent chemoattractant for GPR15-expressing T cells and together they mediate lymphocyte recruitment to the large intestine and skin. GPR15L is constitutively expressed by colon epithelial cells where its expression is minimally altered by intestinal inflammation.  Significant expression of GPR15L is also seen in additional mucosal epithelial cells, including those of the stomach, esophagus, and urinary tract. GPR15L was first identified as an antimicrobial peptide (AMP) due to its broad spectrum of antimicrobial activity, a property shared with many chemokines. GPR15L binds to an additional receptor, SUSD2, and early studies have indicated that both are downregulated in colon cancer tissue resulting in inhibited colon cancer growth. PeproTech’s E.coli-derived Recombinant Human GPR15L consists of 57 amino acid residues and has a calculated molecular weight of 6.5 kDa.

4.重组人PD-1 Fc

产品描述:Programmed cell death protein 1 (PD-1), or CD279, is a type I inhibitory transmembrane receptor of the CD28 receptor family that, along with its B7 family ligands, programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2), belongs to the immunoglobulin superfamily. While other CD28 family members are expressed predominantly in T cells, PD-1 is widely expressed and found in multiple lymphocytes including T cells, B cells, myeloid, and NKT cells upon activation. PD-1 is a negative regulator of immune response, and is referred to as an inhibitory immune checkpoint molecule. Ligation with PD-L1 or PD-L2 results in inhibited activation, proliferation, and cytokine secretion (e.g. IFN-gamma, IL-10) in T cells, ultimately dampening immune response.  PeproTech’s CHO cell-derived Recombinant Human PD-1 Fc is a glycosylated, disulfide-linked homodimer of 501 amino acid residues whose monomer consists of the 268-amino-acid length mature PD-1 sequence fused to the 231-amino-acid length Fc portion of human IgG1 by two glycines. The calculated molecular weight of monomeric CHO cell-derived Recombinant Human PD-1 Fc is 55.3 kDa.

5.无动物成分级别重组人IL-5

产品描述:IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 are cross-species reactive. Recombinant Human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.

6.无动物成分级别重组人MCP-2 (CCL8)

产品描述:The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-2 (CCL8) is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

7.GMP级别重组人Heregulinβ-1

产品描述:Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms releases soluble growth factors. HRG1-β1 contains an Ig domain and an EGF-like domain; the latter is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. This binding induces erb3 and erb4 heterodimerization with erb2, stimulating intrinsic kinase activity that leads to tyrosine phosphorylation. Although HRG1-β1's biological effects are still unclear, it has been found to promote motility and invasiveness of breast cancer cells, which may also involve up-regulation of expression and function of the autocrine motility-promoting factor (AMF).

8.GMP级别重组人PDGF-AA

产品描述:PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. 

9.GMP级别重组人KGF

产品描述:KGF (FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.

10.GMP级别重组人Activin A

产品描述:Activin A is a TGF-β family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival.

11.兔抗人CRP多抗

制备:Produced from sera of rabbits immunized with highly pure Recombinant Human CRP. Anti-Human CRP-specific antibody was purified by affinity chromatography employing an immobilized Human CRP matrix.

免疫原:E.coli-derived, 23.2 kDa Recombinant Human CRP (PeproTech catalog# 350-13)* 

12.兔抗人CRP多抗 生物素标记

制备:Produced from sera of rabbits immunized with highly pure Recombinant Human CRP. Anti-Human CRP-specific antibody was purified by affinity chromatography employing an immobilized Human CRP matrix.

免疫原:E.coli-derived, 23.2 kDa Recombinant Human CRP (PeproTech catalog# 350-13)* 



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